TOP News

Health: COVID-19 booster shots create long-lasting antibody response

US clears updated COVID boosters for kids as young as 5

  US clears updated COVID boosters for kids as young as 5 The U.S. on Wednesday authorized updated COVID-19 boosters for children as young as 5, seeking to expand protection ahead of an expected winter wave. Tweaked boosters rolled out for Americans 12 and older last month, doses modified to target today’s most common and contagious omicron relative. While there wasn't a big rush, federal health officials are urging that people seek the extra protection ahead of holiday gatherings. Now the Food andTweaked boosters rolled out for Americans 12 and older last month, doses modified to target today’s most common and contagious omicron relative. While there wasn't a big rush, federal health officials are urging that people seek the extra protection ahead of holiday gatherings.

While getting a COVID-19 vaccine provides antibodies against the coronavirus, getting a booster shot creates a longer-lasting antibody response, according to new research.

Both of the mRNA vaccine boosters provide enhanced levels of protection, but Moderna's antibody levels exceeded Pfizer's through the five-month study period. File Photo by Debbie Hill/UPI © Debbie Hill/UPI Both of the mRNA vaccine boosters provide enhanced levels of protection, but Moderna's antibody levels exceeded Pfizer's through the five-month study period. File Photo by Debbie Hill/UPI

"These results fit with other recent reports and indicate that booster shots enhance the durability of vaccine-elicited antibodies," said senior researcher Dr. Jeffrey Wilson of the University of Virginia (UVA) Health division of asthma, allergy and immunology, in Charlottesville.

Your Easy Guide To COVID-19 Vaccines In Ontario & How Many Doses You Should Have

  Your Easy Guide To COVID-19 Vaccines In Ontario & How Many Doses You Should Have So many steps it's getting confusing.To give you a hand, we've made a new and easy guide to getting vaccinated in Ontario, based on guidance from Public Heath Ontario. No matter where in the process you might be right now, you can get back on the path.

"Although only about half of the U.S. population that is eligible for a booster has received one, it is increasingly clear that boosters enhance the protection that is conferred by the primary series mRNA vaccines alone," Wilson said in a university news release.

In the study of almost 350 volunteers, getting an mRNA booster (from drugmakers Pfizer or Moderna) made for longer-lasting antibodies for all recipients, the investigators found. That was even true for those who had recovered from a COVID-19 infection.

The researchers worked with 117 UVA employee volunteers who had a booster shot and another 228 volunteers who had just a primary vaccine series of two shots.

The study results revealed similar antibody levels in both groups about one week to 31 days after their shots. The boosted antibodies then lasted longer.

Are the new COVID boosters really better? Here's what early research says

  Are the new COVID boosters really better? Here's what early research says The much talked-up new bivalent COVID-19 vaccine boosters may not be all that superior to the old shots at neutralizing Omicron, two new studies suggest. Both studies are small, together involving just 73 people in total who were followed for about a month. Both are pre-prints that haven’t yet been peer-reviewed. However, their authors say their findings hint at a phenomenon known as “immunological imprinting” — the immune system’s habit of locking onto, and responding to, the first version of the virus it encountered, either by vaccination or infection.

"Our initial thought was that boosters would lead to higher antibody levels than the primary vaccine series, but that was not what we found," said co-author Samuel Ailsworth. "Instead, we found that the booster led to longer-lasting antibodies."

Both of the mRNA vaccine boosters provide enhanced levels of protection, but Moderna's antibody levels exceeded Pfizer's through the five-month study period.

COVID-19 infections were high in the community at the time boosters were being given. In studying those who also had a COVID infection, the researchers found that the "enhanced antibody durability observed after booster vaccination was not explained by hybrid immunity."

Wilson's research team previously found that antibodies from the primary vaccination series made by Pfizer declined faster than those made by Moderna. They also found that older recipients of the Pfizer vaccine generated fewer antibodies than younger recipients, but that difference faded over time. Age wasn't a factor with antibodies in the Moderna vaccine.

Pfizer study says updated COVID boosters rev up protection

  Pfizer study says updated COVID boosters rev up protection Pfizer’s updated COVID-19 booster significantly revved up adults’ virus-fighting antibodies, the company said Friday, releasing early findings from a rigorous study of the new shots. Booster doses tweaked to target the most common omicron strain rolled out in early September, and the Food and Drug Administration said the latest data should spur more Americans to get one — especially before another expected wave of cases as people travel for Thanksgiving. Pfizer said people 55 and older who got the omicron-targeting booster had four-fold higher antibody levels than those given an extra dose of the original vaccine.

The study findings were recently published in the journal Annals of Allergy, Asthma & Immunology.

More information

The U.S. Centers for Disease Control and Prevention has more on COVID-19 boosters.

Copyright © 2022 HealthDay. All rights reserved.

Read More

  • CDC: 90% of children in U.S. infected with COVID-19 at least once
  • White House revives program offering free COVID-19 tests by mail
  • U.S. faces onslaught of viral diseases heading into 2023

COVID-19 booster shots create long-lasting antibody response .
While getting a COVID-19 vaccine provides antibodies against the coronavirus, getting a booster shot creates a longer-lasting antibody response, according to new research. © Debbie Hill/UPI Both of the mRNA vaccine boosters provide enhanced levels of protection, but Moderna's antibody levels exceeded Pfizer's through the five-month study period. File Photo by Debbie Hill/UPI "These results fit with other recent reports and indicate that booster shots enhance the durability of vaccine-elicited antibodies," said senior researcher Dr.

See also