Sport: College football odds, lines, bets, predictions for Week 13, 2021: Computer model picks Oklahoma State, Oregon

There's nothing like rivalry week in college football, and the Week 13 college football schedule is loaded. The Week 13 college football odds from Caesars Sportsbook has No. 2 Ohio State favored by 8.5 points against No. 5 Michigan, No. 3 Alabama at -19.5 against Auburn (3:30 p.m. ET, CBS) and No. 7 Oklahoma State favored by four against No. 10 Oklahoma in three of the week's biggest matchups. And there are plenty of games that, while they might not have College Football Playoff considerations, still have plenty on the line for each team.

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Derek Mason Vanderbilt

No. 11 Oregon (-7) vs. Oregon State, Virginia (-7) vs. Virginia Tech, No. 14 Wisconsin (-7) vs. Minnesota, and No. 20 NC State (-6) vs. North Carolina are just some of the Week 13 college football spreads that should be intriguing to casual fans and bettors alike. Which should you add to your Week 13 college bets? Before making any Week 13 college football picks, be sure to see the latest college football predictions and betting advice from SportsLine's proven model.

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SportsLine's advanced model locked in its Week 11 NFL picks for every game on the NFL scheduleSan Francisco 49ers tight end George Kittle (85) during Super Bowl LIV against the Kansas City Chiefs at Hard Rock Stadium.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Week 13 of the 2021 season on a 39-25 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest Week 13 college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.

Top Week 13 college football predictions

One of the top college football picks the model is recommending for Week 13: No. 7 Oklahoma State (-3.5) covers against No. 10 Oklahoma in the 2021 Bedlam Series rivalry matchup at 7:30 p.m. ET on Saturday. Oklahoma has the overwhelming advantage in total and recent history on its side with a 90-18 record in the series and wins in the previous six matchups.

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Barrett Sallee has locked in his top three college football picks for Week 12 : He's backing No. 10 Wake Forest (+4.5) at Clemson in a noon ET kickoff in the ACC. The Demon Deacons have a chance to clinch the ACC Atlantic Division title on Saturday afternoon. They have been one of the highest-scoring teams in the country, averaging 44.7 points per game. Quarterback Sam Hartman ranks eighth nationally with 30 touchdown passes.Wake Forest is facing a Clemson offense that has struggled under quarterback DJ Uiagalelei. His 107.

In this matchup on Saturday night, Oklahoma State can finally claim victory in a game it has sorely wanted to win for years. After years of not being able to match up with the Sooners' high-octane offense, the Pokes might finally have a unit to match. Oklahoma State's defense ranks fourth in the nation in yards per carry allowed and 14th in yards per pass attempt allowed.

SportsLine's model has Oklahoma State winning and covering the spread in more than 60 percent of simulations, making it a top pick for rivalry week college football bets. The point total sits at 49.5, and SportsLine's simulations have that going over well over 50 percent of the time.

Another one of the college football predictions from the model: No.11 Oregon (-7) takes care of business against Oregon State in a 3:30 p.m. ET matchup on Saturday. The Ducks will be looking to bounce back from a loss to Utah and continue their 18-game home winning streak on Saturday afternoon. They still have plenty to play for, as a win in this game would clinch their spot in the Pac-12 title game. Oregon has won eight of the last 10 meetings in this series, including a 24-10 win at home two years ago.

Oregon vs. Saint Mary's odds, line: 2021 college basketball picks, Nov. 23 predictions from proven model

SportsLine's model just revealed its college basketball picks for Oregon vs. Saint Mary's in the 2021 Maui InvitationalMar 20, 2019; Salt Lake City, UT, USA; General overall view of a basketball approaching the rim and net before the first round of the 2019 NCAA Tournament at Vivint Smart Home Arena.

The Ducks are led by running back Travis Dye, who has rushed for 937 yards and 12 touchdowns on 158 carries. He will be facing an Oregon State run defense that is allowing more than four yards per attempt. SportsLine's model projects Dye to rush for nearly 90 yards and one touchdown in this game, which is one reason why the Ducks are covering the spread in 60 percent of simulations.

How to make Week 13 college football picks

The model has also made the call on who wins and covers in every other game on the Week 13 college football schedule, and it's also calling for a top College Football Playoff contender to get a huge scare from a big underdog. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence? And which underdog do you need to jump on now? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $3,700 in profit over the past five-plus seasons, and find out.

Week 13 college football odds (via Caesars)

Here are the college football lines for some of Week 13's most notable matchups:

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Thursday, Nov. 25

Fresno State vs. San Jose State (+7.5, 52.5)

Ole Miss vs. Mississippi State (-1, 60.5)

Friday, Nov. 26

Boise State vs. San Diego State (+2.5, 44)

Iowa vs. Nebraska (-3.5, 44.5)

Missouri vs. Arkansas (-14, 62.5)

Cincinnati vs. East Carolina (+14, 58)

Colorado vs. Utah (-24, 52.5)

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SportsLine's advanced model locked in its Week 12 NFL picks for every game on the NFL scheduleSan Francisco 49ers tight end George Kittle (85) during Super Bowl LIV against the Kansas City Chiefs at Hard Rock Stadium.

UNC vs. NC State (-7, 63)

Saturday, Nov. 27

Wake Forest vs. Boston College (+5, 64.5)

Houston vs. UConn (+32.5, 57.5)

Georgia vs. Georgia Tech (+35, 54.5)

Ohio State vs. Michigan (+8, 64)

Texas Tech vs. Baylor (-14, 52)

UTSA vs. North Texas (+12, 59.5)

Penn State vs. Michigan State (-1.5, 52.5)

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Oregon State vs. Oregon (-7, 61)

Alabama vs. Auburn (+19.5, 55)

Wisconsin vs. Minnesota (+6.5, 39)

Texas A&M vs. LSU (+6.5, 45.5)

Pittsburgh vs. Syracuse (+11, 58.5)

Oklahoma vs. Oklahoma State (-3.5, 51.5)

Notre Dame vs. Stanford (+17, 52.5)

BYU vs. USC (+7, 64)